Ingredient Pairings
N-Acetylcysteine (NAC) and Quercetin are declared together 7.38x more often than chance would predict, among 65,854 on-market DSLD products.
For every pair of compounds we track, we compare how often they're actually declared on the same label to how often you'd expect by chance alone, given how common each one is on its own. A pair with a lift of 3x shows up on the same label three times as often as random chance would predict; a lift below 1x means the pair actually avoids each other, more often found on separate products than together. Only pairs declared together on at least 100 products are included, to keep small-sample noise out of the rankings.
Most disproportionate pairings
The pairs that travel together far more than their individual popularity alone would explain — the closest thing DSLD data has to visible "stacks."
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| Pair | Lift | Together | % of A's products | % of B's products |
|---|---|---|---|---|
| N-Acetylcysteine (NAC) + Quercetin | 7.38x | 389 | 25.1% | 17.4% |
| L-Theanine + Melatonin | 7.11x | 349 | 17.5% | 21.6% |
| Copper + Manganese | 6.61x | 5,076 | 74.7% | 68.2% |
| Caffeine + Creatine | 6.53x | 833 | 19.4% | 42.5% |
| Manganese + Selenium | 6.25x | 5,501 | 73.9% | 70.7% |
| Thiamine (Vitamin B1) + Riboflavin (Vitamin B2) | 6.06x | 9,060 | 91.4% | 91.2% |
| Copper + Selenium | 6.06x | 4,871 | 71.7% | 62.6% |
| Copper + Iodine | 5.88x | 4,389 | 64.6% | 60.6% |
| Iodine + Manganese | 5.79x | 4,737 | 65.5% | 63.6% |
| Chromium + Manganese | 5.72x | 5,239 | 64.7% | 70.4% |
| Copper + Vitamin K | 5.72x | 2,824 | 41.6% | 59.0% |
| Manganese + Vitamin K | 5.7x | 3,082 | 41.4% | 64.4% |
| Copper + Lutein | 5.65x | 1,455 | 21.4% | 58.3% |
| Iodine + Selenium | 5.64x | 4,829 | 66.7% | 62.0% |
| Chromium + Selenium | 5.54x | 5,310 | 65.5% | 68.2% |
| Iodine + Vitamin K | 5.49x | 2,887 | 39.9% | 60.3% |
| Glycine + N-Acetylcysteine (NAC) | 5.46x | 203 | 12.9% | 13.1% |
| Lutein + Selenium | 5.44x | 1,606 | 64.3% | 20.6% |
| Thiamine (Vitamin B1) + Pantothenic Acid (Vitamin B5) | 5.43x | 8,191 | 82.7% | 81.6% |
| Pantothenic Acid (Vitamin B5) + Biotin (Vitamin B7) | 5.4x | 7,826 | 78.0% | 82.2% |
| Riboflavin (Vitamin B2) + Pantothenic Acid (Vitamin B5) | 5.38x | 8,148 | 82.0% | 81.2% |
| Chromium + Copper | 5.37x | 4,489 | 55.4% | 66.1% |
| Selenium + Vitamin K | 5.36x | 3,031 | 38.9% | 63.4% |
| Lutein + Vitamin K | 5.33x | 967 | 38.7% | 20.2% |
| Iodine + Biotin (Vitamin B7) | 5.19x | 5,431 | 75.0% | 57.0% |
| Chromium + Iodine | 5.18x | 4,611 | 56.9% | 63.7% |
| Riboflavin (Vitamin B2) + Biotin (Vitamin B7) | 5.08x | 7,288 | 73.4% | 76.6% |
| Thiamine (Vitamin B1) + Biotin (Vitamin B7) | 5.06x | 7,246 | 73.1% | 76.1% |
| Lutein + Manganese | 5.05x | 1,425 | 57.1% | 19.1% |
| Collagen (Hydrolyzed Collagen Peptides) + Glucosamine | 5x | 213 | 13.1% | 12.4% |
Most common pairings
Ranked by raw count instead of lift — mostly multivitamin and B-complex staples that are common individually, so their high overlap isn't necessarily surprising.
| Pair | Together | Lift |
|---|---|---|
| Vitamin B12 (Cobalamin) + Vitamin B6 (Pyridoxine) | 12,063 | 3.62x |
| Vitamin B12 (Cobalamin) + Folate (Vitamin B9) | 10,613 | 4.15x |
| Vitamin B6 (Pyridoxine) + Folate (Vitamin B9) | 10,471 | 3.82x |
| Niacin (Vitamin B3) + Vitamin B6 (Pyridoxine) | 10,377 | 3.63x |
| Vitamin B6 (Pyridoxine) + Vitamin C | 10,153 | 2.21x |
| Calcium + Magnesium | 10,078 | 2.28x |
| Vitamin C + Zinc | 9,887 | 2.47x |
| Vitamin B12 (Cobalamin) + Niacin (Vitamin B3) | 9,874 | 3.71x |
| Vitamin A + Vitamin C | 9,862 | 2.89x |
| Vitamin B12 (Cobalamin) + Vitamin C | 9,558 | 2.23x |
| Calcium + Vitamin C | 9,507 | 1.6x |
| Pantothenic Acid (Vitamin B5) + Vitamin B6 (Pyridoxine) | 9,393 | 4.02x |
| Calcium + Potassium | 9,365 | 2.55x |
| Thiamine (Vitamin B1) + Vitamin B6 (Pyridoxine) | 9,284 | 4.02x |
| Riboflavin (Vitamin B2) + Vitamin B6 (Pyridoxine) | 9,270 | 4x |
| Vitamin C + Vitamin E | 9,083 | 2.57x |
| Thiamine (Vitamin B1) + Riboflavin (Vitamin B2) | 9,060 | 6.06x |
| Calcium + Vitamin D | 8,947 | 1.98x |
| Thiamine (Vitamin B1) + Vitamin B12 (Cobalamin) | 8,933 | 4.15x |
| Thiamine (Vitamin B1) + Niacin (Vitamin B3) | 8,911 | 4.83x |
Pairs that avoid each other
The other direction: compounds that show up on the same label less often than chance would predict — often a sign they belong to different product categories (a stimulant-focused pre-workout vs. a basic multivitamin, for instance) rather than any real incompatibility.
| Pair | Lift | Together |
|---|---|---|
| Caffeine + Iron | 0.19x | 109 |
| Caffeine + Vitamin A | 0.22x | 165 |
| Caffeine + Manganese | 0.23x | 112 |
| Caffeine + Selenium | 0.24x | 123 |
| Caffeine + Zinc | 0.28x | 240 |
| Omega-3 Fatty Acids (EPA + DHA) + Potassium | 0.3x | 254 |
| Caffeine + Vitamin E | 0.3x | 233 |
| Creatine + Vitamin A | 0.31x | 104 |
| Caffeine + Vitamin D | 0.31x | 308 |
| Melatonin + Zinc | 0.31x | 103 |
| Calcium + Omega-3 Fatty Acids (EPA + DHA) | 0.33x | 451 |
| Caffeine + Copper | 0.33x | 146 |
| Creatine + Zinc | 0.34x | 136 |
| Caffeine + Iodine | 0.34x | 162 |
| L-Theanine + Vitamin D | 0.34x | 156 |