Supplement Label Index

D-Alpha-Tocopheryl Succinate (natural, esterified) vs. Mixed Tocopherols

Among 4,796 on-market vitamin e products with an identifiable primary form, 56.8% use D-Alpha-Tocopheryl Succinate (natural, esterified) (2,726 products) and 7.1% use Mixed Tocopherols (341).

D-Alpha-Tocopheryl Succinate (natural, esterified)Mixed Tocopherols
Quality tierTier 1Unrated
Vitamin E by weight
Share of market56.8%7.1%
On-market products2,726341
Median declared dose34 mg
middle half: 20–90
40 mg
middle half: 11.5–118.42
Most common brandsDC, Douglas Laboratories, Source NaturalsPerque, Futurebiotics, Allergy Research Group

Doses are declared per serving in mg. “By weight” is the share of the ingredient that is the nutrient itself (e.g. elemental magnesium in a magnesium salt).

Why D-Alpha-Tocopheryl Succinate (natural, esterified) is tier 1

Same rationale as the acetate ester -- esterification does not meaningfully change post-hydrolysis bioavailability; natural-form advantage over synthetic still applies.

Source: Burton GW et al. 1998, PMID 9537614

Why Mixed Tocopherols is unrated

A mixed alpha/beta/gamma/delta blend has different overall biological activity than isolated alpha-tocopherol (RDA/label math counts only the alpha fraction), but no comparative-potency study for this specific commercial blend was verified.

Source: uncertain -- needs review

Tiers summarize published comparative bioavailability or outcome evidence for each form (see methodology). This page describes the market; it is not a recommendation to take either form. Talk to a clinician about what's right for you.

Other vitamin e comparisons