Supplement Label Index

Zinc Oxide vs. Zinc Citrate

Among 8,549 on-market zinc products with an identifiable primary form, 29% use Zinc Oxide (2,481 products) and 26% use Zinc Citrate (2,223).

Zinc OxideZinc Citrate
Quality tierTier 3Tier 1
Zinc by weight80.3%32.1%
Share of market29%26%
On-market products2,4812,223
Median declared dose15 elemental mg
middle half: 8–23.6
8 elemental mg
middle half: 4–15
Most common brandsNew Chapter, GNC Mega Men, GNC Women's Ultra MegaNature's Way, SmartyPants, Metagenics

Doses are declared per serving in elemental mg. “By weight” is the share of the ingredient that is the nutrient itself (e.g. elemental magnesium in a magnesium salt).

Why Zinc Oxide is tier 3

Isotope-tracer RCT: absorption 49.9%, significantly lower than citrate/gluconate; 3/15 subjects showed little/no absorption.

Source: Wegmuller R et al. 2014, PMID 24259556

Why Zinc Citrate is tier 1

Isotope-tracer RCT: absorption 61.3%, comparable to gluconate, significantly higher than oxide.

Source: Wegmuller R et al. 2014, J Nutr 144(2):132-136, PMID 24259556

Tiers summarize published comparative bioavailability or outcome evidence for each form (see methodology). This page describes the market; it is not a recommendation to take either form. Talk to a clinician about what's right for you.

Other zinc comparisons