Manganese Sulfate vs. Manganese Gluconate
Among 4,675 on-market manganese products with an identifiable primary form, 27.9% use Manganese Sulfate (1,306 products) and 24.9% use Manganese Gluconate (1,162).
| Manganese Sulfate | Manganese Gluconate | |
|---|---|---|
| Quality tier | Tier 2 | Tier 2 |
| Manganese by weight | 32.5% | 12.3% |
| Share of market | 27.9% | 24.9% |
| On-market products | 1,306 | 1,162 |
| Median declared dose | 2,000 elemental mcg middle half: 2,000–2,500 | 2,000 elemental mcg middle half: 1,000–3,000 |
| Most common brands | GNC Mega Men, GNC Women's Ultra Mega, 21st Century | Emergen-C, DC, Wonder Laboratories |
Doses are declared per serving in elemental mcg. “By weight” is the share of the ingredient that is the nutrient itself (e.g. elemental magnesium in a magnesium salt).
Why Manganese Sulfate is tier 2
NIH ODS states no human comparative bioavailability data exist across manganese forms; treated as "acceptable by convention" (soluble reference salt used in mostly-animal research), not evidence-ranked.
Source: https://ods.od.nih.gov/factsheets/Manganese-HealthProfessional/
Why Manganese Gluconate is tier 2
Same caveat -- no human comparative bioavailability data located; acceptable by convention only.
Source: https://ods.od.nih.gov/factsheets/Manganese-HealthProfessional/