Manganese Amino Acid Chelate vs. Manganese Gluconate
Among 4,675 on-market manganese products with an identifiable primary form, 28% use Manganese Amino Acid Chelate (1,309 products) and 24.9% use Manganese Gluconate (1,162).
| Manganese Amino Acid Chelate | Manganese Gluconate | |
|---|---|---|
| Quality tier | Unrated | Tier 2 |
| Manganese by weight | 27.0% | 12.3% |
| Share of market | 28% | 24.9% |
| On-market products | 1,309 | 1,162 |
| Median declared dose | 2,000 elemental mcg middle half: 1,000–4,800 | 2,000 elemental mcg middle half: 1,000–3,000 |
| Most common brands | NOW, XYMOGEN, Bluebonnet | Emergen-C, DC, Wonder Laboratories |
Doses are declared per serving in elemental mcg. “By weight” is the share of the ingredient that is the nutrient itself (e.g. elemental magnesium in a magnesium salt).
Why Manganese Amino Acid Chelate is unrated
Animal (poultry) data suggest higher relative bioavailability than MnSO4, but NIH ODS confirms no human data exist -- not willing to assert a human-relevant tier on animal-only evidence.
Source: uncertain -- needs review (animal/poultry evidence only)
Why Manganese Gluconate is tier 2
Same caveat -- no human comparative bioavailability data located; acceptable by convention only.
Source: https://ods.od.nih.gov/factsheets/Manganese-HealthProfessional/