Grape Seed Extract
Of 2,654 on-market grape seed extract products in the January 2026 DSLD dump, the median declared dose is 50 mg, and 89.0% list unspecified/undisclosed form as the primary form.
Form share
Of 2,589 products with an identifiable primary form, here is the share held by each form of Grape Seed Extract on the market today.
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| Form | Quality tier | n | Share |
|---|---|---|---|
| unspecified/undisclosed form | Unrated | 2,303 | 89.0% |
| OPC / Proanthocyanidins | Unrated | 286 | 11.0% |
Form share over time
Entry-year breakdown of the top forms, 2012–2025.
Dose distribution
Deciles of declared dose per serving (mg), among 1,450 products with a disclosed amount.
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- 39.0% of products fall below the fairy-dust threshold (30 mg, 20% of the studied low dose).
- 44.7% of products don't disclose an amount because Grape Seed Extract is declared inside a proprietary blend.
Where does your dose rank?
Enter a per-serving dose (mg) to see exactly how it compares to the 1,450 on-market grape seed extract products with a disclosed amount. The chart above groups doses into deciles; this looks up the exact percentile for one number.
By dosage form
By target group
Top brands
Search interest over time
How often people search for grape seed extract on Google, US only, the last 5 years. This is public interest, not DSLD label data — a spike here doesn't necessarily line up with anything on this page, and Google's own index (100 = that term's peak popularity in the chosen window) is relative, not an absolute search-volume count.
Or see this search directly on trends.google.com.
Forms explained
Label discloses only the extract (mg) with no standardization; OPC/polyphenol content, which drives potency, is unknown.
Typical standardization: Standardized to OPC / proanthocyanidins; percentage varies by product (label examples cite 95%, "95% extract", procyanidolic value 95). Extracts declared by total polyphenols are not separable (bare "Polyphenols" is also an ordinary row name) and resolve to the unspecified form
Standard commercial specification; the BP/metabolic RCTs dosed 150-600 mg/day of extracts described as polyphenol/proanthocyanidin-rich and one 300 mg/day trial found no significant ambulatory BP effect, but no trial compared standardization levels at equal dose, so standardized vs unstandardized is not ranked.
Source: Sivaprakasapillai B et al. 2009, Metabolism 58(12):1743-1746, PMID 19608210; Ras RT et al. 2013, Br J Nutr 110(12):2234-2241, PMID 23702253; Zhang H et al. 2016, Medicine (Baltimore) 95(33):e4247, PMID 27537554
Reference values
- RDA (adult): not established — Botanical extract, not an essential nutrient; no DRI exists.
- Tolerable Upper Intake Level (adult): not established — Not established -- no IOM/NASEM UL exists; no safety ceiling was verified in this pass.
- Studied clinical dose range: 150–600 mg
- Sivaprakasapillai B et al. 2009, Metabolism 58(12):1743-1746, PMID 19608210 -- RCT in metabolic syndrome, placebo vs 150 mg/day vs 300 mg/day GSE x4 weeks; systolic and diastolic ambulatory BP lower than placebo. Kar P et al. 2009, Diabet Med 26(5):526-531, PMID 19646193 -- double-blind randomized crossover, n=32 type 2 diabetes, 600 mg/day x4 weeks; significant improvements in fructosamine (glycaemia), an inflammation marker and one oxidative-stress marker (whole-blood GSH), and a decrease in total cholesterol. Meta- analysis: Zhang H et al. 2016, Medicine (Baltimore) 95(33):e4247, PMID 27537554 -- 16 trials/810 subjects; SBP -6.08 and DBP -2.80 mmHg, larger in obese/younger/metabolic- syndrome subjects. Counter-evidence: Ras RT et al. 2013, Br J Nutr 110(12):2234-2241, PMID 23702253 -- n=70, 300 mg/day x8 weeks, no significant ambulatory BP effect.
- Note: Standardization is handled like ashwagandha/curcumin: unit_basis stays on the declared extract mg, and the standardization (OPC/proanthocyanidin %, or total polyphenols), which usually appears in raw_form, is carried by a form (OPC/proanthocyanidins) rather than converted; polyphenol-declared extracts resolve to the unspecified form because bare "Polyphenols" cannot be a form alias without capturing unrelated rows. OPC content varies by product, so dose per mg of extract is not comparable across labels without it. "Pycnogenol" (pine bark), "Grape Seed Oil", "Grapeseed Pyruvate", whole-grape/red-wine proanthocyanidin products (BioVin, "Red Wine Proanthocyanidins") and bare "Proanthocyanidins" (source unknown, often cranberry) are NOT grape seed extract and are not aliased. Bare "Grape Seed" is also not aliased: it fuzzy-matches "Grape Seed Oil". Known matcher caveat (dry run, ~5% of this compound's rows): because the alias "grape seed extract" is itself similar in length to "grape extract", the fuzzy step also maps generic "Grape Extract", "Grape (Vitis vinifera) extract", "Vitis vinifera extract" and "Grape fruit seed extract" (grapefruit seed) here; all are flagged needs_review. A reject rule in match_ingredients.py (like _NOT_OMEGA3) requiring "seed" in the row name, and excluding "grape fruit seed", would remove them.