claim: The information provided on this site is for informational purposes only and is not intended as a substitute for advice from your physician or other health care professional or any information contained on or in any product label or packaging.
warning: You should not use the information on this site for diagnosis or treatment of any health problem or for prescription of any medication or other treatment. You should consult with a healthcare professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health program. You should not stop taking any medication without first consulting your physician.
other: Foundation for Longer Life
claim: The use of diets high in collagen to improve bone health dates back to ancient cultures.
other: Life Extension brings you this exciting formulation with KoAct(R), a patented chelated form of calcium and collagen designed to maintain optimal bone health.
other: KoAct(R) helps maintain bone strength and mineral density.1
claim: This remarkable ingredient allows for greater strength and flexibility, so your bones can absorb energy, reducing the risk of age-related injuries.
other: Additional plant extracts from bamboo and dried plum have also been added for bone-protective minerals and polyphenols.2-8
other: Bone Strength Formula with KoAct(R) contains the following ingredients:
Vitamin D3
~ Facilitates absorption of calcium into the bloodstream.
~ Regulates how much calcium enters and leaves bone tissue.
~ Helps regulate healthy cell division and differentiation.
~ Functions as a vital co-factor in bone mineralization through the absorption of calcium and phosphorus.
Calcium
~ KoAct(R) is a unique patented chelated compound of calcium and hydrolyzed collagen peptides (type I collagen) designed to enhance collagen support and turnover while supporting optimal bone mineral density and strength.
Magnesium
~ A critical component of our skeletin, with 50-60% of totally body magnesium found in bone
~ Positively influences the bone mineral matrix and its ability to metabolize minerals needed for repair and rebuilding.
Silicon
~ Plays an important role in bone formation through the synthesis and/or stabilization of collagen.
Dried Plu
~ Supports osteoblas (bone building cells) activity and function by upregulating cell-signaling compounds (Runx2, Osterix and IGF-1) and enhancing expression of an enzyme (lysyl oxidase) that is involved in collagen cross-linking.
Boron
~ Impacts steroid hormone metabolism - affecting the levels of estrogens and testosterone.
other: If you need extra bone support, ask your healthcare professional how Bone Strength Formula with KoAct(R) can be part of a comprehensive nutritional program in conjunction with proper resistance exercise. Life Extension offers several mineral formulas that may complement Bone Strength Formula with KoAct(R) to ensure optimal mineral intake.
claim: If you have any questions about this, please call a Life Extension Health Advisor who can help to tailor a supplement program that meets your individual bone-care needs at 1-800-226-2370.
other: KoAct(R) is a registered trademark of AIDP, Inc.
Fruitex B(R) and OsteoBoron(R) are registered trademarks of VDF Futureceuticals, Inc. U.S. Patent No. 5,962,049.
other: Dosage and Use ~ Take four capsules daily in divided doses with or without food, or as recommended by a healthcare practitioner.
warning: Warnings
~ Keep out of reach of children
warning: ~ Do not exceed recommended dose
~ Do not purchase if outer seal is broken or damaged.
warning: ~ When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating
other: All contents Copyright (C) 1995-2013 Life Extension(R) All rights reserved
other: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
claim: References
1. Hooshmand 5 et al. Evidence for bone reversal properties of a calcium-collagen chelate, a novel dietary supplement. J Food Nutr Disor. 2013;2(1):1-6.
2. Jugdaohsingh R et al. Dietary Silicon Intake is Positively Associated with Bone Mineral Density In Men and Premenopausal Women of the Framingham Offspring Cohort. J Bone Miner Res. 2004;19(2):297-307.
3. Arjmandi BH, Khalil DA, Lucas EA, et al. Dried plums improve indices of bone formatino in postmenopausal women. J Womens Health Gend Based Med. 2002 Jan;11(1):61-8.
4. Bu SY, Lerner M, Stoecker BJ, et al. Dried plum polyphenols inhibit osteoclastogenesis by down-regulating NFATc1 and inflammatory mediators. Calcif Tissue Int. 2008 Jun;82(6):475-88.
5. Franklin M, BuSY, Lerner MR, et al. Dried Plum prevents bone loss in a male osteoporosis model via IGF-I and the RANK pathway. Bone.2006 Dec;39(6):1331-42.
6. Bu Sy, Hunt TS, Smith BJ. Dried plum polyphenols attenuate the detrimental effects of TNF-alpha on osteoblast function coincident with up-regulation of Runx2, osterix and IGF-I. J Nutr biochem. 2009 Jan;20(1):35-44.
7. Bu Sy, Lucas EA, Franklin M, et al. Comparison of dried plum supplementation and intermittent PTH in restoring bone in osteopenic orchidectomized rats. Osteoporos Int. 2007 Jul;18(7):931-42.
8. Deyhim F, Stoecker BJ, Brusewitz GH, Devareddy L, Arjimandi BH. Dried plum reverses bone loss in an osteopenic rat model of osteoporosis. Menopause. 2005 Nov;12(67):755-62.
Label facts as declared by the manufacturer to the NIH Dietary Supplement Label Database (DSLD), not independently
lab-tested. This page reports what the label says; it does not rate, score, or recommend this product.